
Key Takeaways
- Peptic ulcers are open sores that develop on the inside lining of your stomach and the upper portion of your small intestine.
- While stress alone doesn't directly cause ulcers, chronic stress can worsen symptoms and increase your risk by raising stomach acid levels and weakening your immune system.
- The most common causes of peptic ulcers are infection with Helicobacter pylori (H. pylori) bacteria and the long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and aspirin.
- Newtown Gastroenterology provides advanced, compassionate digestive healthcare in NYC. If you're experiencing stomach pain, schedule an appointment to get the expert care you need.
Understanding Peptic Ulcers
A peptic ulcer is an open sore that forms when stomach acid erodes the protective lining of your digestive tract. This can happen in the stomach (a gastric ulcer) or the upper part of the small intestine (a duodenal ulcer).
For years, it was widely believed that stress, spicy foods, and a hectic lifestyle were the primary culprits behind ulcers. While these factors can certainly aggravate an existing ulcer, we now know they aren't the root cause. The two main culprits are:
- Helicobacter pylori (H. pylori): This bacterium lives in the mucous layer that protects the lining of the stomach and small intestine. Often, it causes no problems, but it can lead to inflammation and eventually cause an ulcer to form.
- Long-term use of NSAIDs: Nonsteroidal anti-inflammatory drugs (NSAIDs) can irritate and disrupt the stomach's natural defense against acid. This includes common over-the-counter medications.
Common NSAIDs That Can Contribute to Ulcers
- Ibuprofen (Advil, Motrin)
- Naproxen sodium (Aleve)
- Aspirin
- Diclofenac
If you regularly take these medications for conditions like arthritis or chronic pain, it's important to discuss the risk of ulcers with your doctor. Newtown Gastroenterology can work with you to find safer alternatives or develop a plan to protect your stomach lining.
How Do Stress and Certain Medications Affect Ulcers?
While H. pylori and NSAIDs are the direct causes, other factors can significantly increase your risk or make an existing ulcer worse. This is where stress and specific medications come into play.
The Role of Chronic Stress
Chronic stress doesn't create ulcers on its own, but it can be a powerful contributing factor. When you're under constant stress, your body is in a continuous 'fight or flight' mode. This state can:
- Increase Stomach Acid Production: Stress can cause your stomach to produce more acid, which can irritate the stomach lining and worsen the pain of an existing ulcer.
- Weaken the Immune System: Prolonged stress weakens your immune response, making you more susceptible to infections like H. pylori.
- Encourage Unhealthy Habits: People under stress are more likely to smoke, drink alcohol excessively, or rely on NSAIDs for stress-related headaches, all of which are known risk factors for ulcers.
The Impact of Medications on Ulcer Risk
Besides NSAIDs, other medications can also increase your risk of developing peptic ulcers, especially when combined with other risk factors.Certain medications can increase the risk of developing ulcers or exacerbate existing ulcers. Below is a breakdown of these drugs and their effects:
- Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
NSAIDs are a common cause of ulcers as they can irritate the stomach lining and disrupt protective mechanisms that prevent ulcer formation. Examples of NSAIDs include ibuprofen and aspirin. - Corticosteroids
These can raise the likelihood of ulcers, especially when taken in combination with NSAIDs. Examples of corticosteroids include prednisone and cortisone. - Anticoagulants (Blood Thinners)
While anticoagulants do not cause ulcers directly, they significantly increase the risk of bleeding from an existing ulcer, which can lead to life-threatening complications. Examples of these drugs include warfarin (Coumadin) and apixaban (Eliquis). - Selective Serotonin Reuptake Inhibitors (SSRIs)
Some research suggests that SSRIs may heighten the risk of upper gastrointestinal bleeding, especially when used alongside NSAIDs. Common SSRIs include fluoxetine (Prozac) and sertraline (Zoloft).
Understanding how these medications impact gastrointestinal health is essential for minimizing risks and managing potential complications. Always consult with a healthcare provider when combining these drugs or managing conditions requiring their use.
Get Expert Ulcer Diagnosis and Treatment at Newtown Gastroenterology
Don't let persistent stomach pain control your life. Newtown Gastroenterology offers comprehensive care for peptic ulcers, from accurate diagnosis using advanced tools like endoscopy to effective treatment plans tailored to your specific needs.
Ready to find relief? Schedule an appointment today to discuss your symptoms with our board-certified gastroenterologists.
Frequently Asked Questions
Can stress cause an ulcer to bleed?
While stress doesn't directly cause an ulcer, it can exacerbate the condition. Increased stomach acid and unhealthy coping mechanisms associated with stress (like drinking alcohol or smoking) can irritate an existing ulcer and potentially lead to bleeding.
What are the first signs of a stomach ulcer?
The most common symptom of a peptic ulcer is burning stomach pain. This pain may feel worse between meals or at night, can come and go for days or weeks, and might be temporarily relieved by eating certain foods or taking an antacid. Other signs include bloating, heartburn, and nausea.
How do I know if my stomach pain is from an ulcer or just stress?
It can be difficult to tell the difference on your own. Stress can cause stomach upset and discomfort, but the pain from an ulcer is typically a distinct, localized burning sensation. If your stomach pain is persistent, severe, or accompanied by symptoms like weight loss, vomiting, or dark, tarry stools, it's crucial to see a doctor for a proper diagnosis.
How are peptic ulcers treated?
Treatment depends on the cause. If the ulcer is caused by an H. pylori infection, your doctor will prescribe a course of antibiotics. If NSAID use is the cause, you will be advised to stop taking the medication. Additionally, your doctor will likely prescribe acid-blocking medications, such as proton pump inhibitors (PPIs) or H2 blockers, to reduce stomach acid and allow the ulcer to heal.